SCHEMBL10945757

SCHEMBL10945757

O=C=NCc1ccc(C2CCC(N=C=O)CC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
SPHK1 Q9NYA1 3/20 0.35
CYP3A4 P08684 2/20 0.32
ESR1 P03372 1/20 0.30
CYP2C9 P11712 1/20 0.30
ESR2 Q92731 1/20 0.30
FFAR1 O14842 1/20 0.30
LSS P48449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11121831 0.80 ALDH1A1 (0.41) ALDH1A1SPHK1ESR2
SCHEMBL28947504 0.80 ALDH1A1 (0.43) ALDH1A1SPHK1CYP3A4ESR1CYP2C9
SCHEMBL7414530 0.76 SLC18A3 (0.44) ALDH1A1
SCHEMBL4040088 0.76 SLC18A3 (0.44) ALDH1A1
SCHEMBL9351603 0.76 CYP3A4 (0.40) ALDH1A1CYP3A4ESR2
SCHEMBL21089 0.73 MIF (0.44) ALDH1A1CYP3A4
SCHEMBL11045325 0.72 ALDH1A1 (0.33) ALDH1A1CYP3A4
Cyclohexane SCHEMBL28302863 0.71 MIF (0.40) ALDH1A1CYP3A4
Water SCHEMBL14972874 0.71 MIF (0.43) ALDH1A1CYP3A4
SCHEMBL22471901 0.71 MIF (0.43) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4547454-A Photosensitive multi-layer material and preparation of adhesive layers employed therein BASF AKTIENGESELLSCHAFT (DE) 1985-10-15 US disclosed