Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16198301 | 0.82 | GAA (0.48) | GAANPC1CYP3A4ALDH1A1TDP1 | |
| SCHEMBL1911832 | 0.80 | ALDH1A1 (0.50) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL17736226 | 0.80 | ALDH1A1 (0.52) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL10948454 | 0.79 | NPC1 (0.56) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL27477446 | 0.78 | GAA (0.45) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL17744292 | 0.78 | ERN1 (0.55) | GAANPC1CYP3A4ALDH1A1ERN1 | |
| SCHEMBL16659617 | 0.78 | CYP3A4 (0.50) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL8709585 | 0.78 | GAA (0.48) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL9563947 | 0.76 | ALDH1A1 (0.52) | GAANPC1G6PDCYP3A4ALDH1A1 | |
| SCHEMBL5048480 | 0.76 | NPC1 (0.52) | GAANPC1G6PDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | claimed |
| EP-0069907-B1 | PROCESS FOR PREPARING M-CHLORO-SUBSTITUTED ANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| US-4495368-A | Process for the preparation of meta-halogenoanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4460788-A | Process for preparation of anilines which are m-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0051782-B1 | PROCESS FOR THE MANUFACTURE OF M-HALOGENATED ANILINES | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4429156-A | Process for the preparation of m-halogen-substituted anilines | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0051782-A1 | Process for the manufacture of m-halogenated anilines | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |