(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL10948488

C(=C/c1ccccc1)\c1ccccc1.c1ccc2[nH]cnc2c1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.53
KDM4E B2RXH2 6/20 0.51
MEN1 O00255 5/20 0.51
KMT2A Q03164 5/20 0.51
RAB9A P51151 5/20 0.51
ALDH1A1 P00352 4/20 0.51
NPC1 O15118 4/20 0.51
HPGD P15428 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
PKM P14618 2/20 0.51
HSP90AA1 P07900 1/20 0.51
IP6K1 Q92551 2/20 0.51
IP6K3 Q96PC2 1/20 0.51
IP6K2 Q9UHH9 1/20 0.51
MAPT P10636 2/20 0.50
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
GLA P06280 1/20 0.44
MAPK1 P28482 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL29239809 1.00 TAAR1 (0.53) TAAR1KDM4EMEN1KMT2ARAB9A
(Z)-1,2-Diphenylethene SCHEMBL10948499 1.00 TAAR1 (0.53) TAAR1KDM4EMEN1KMT2ARAB9A
Benzimidazole SCHEMBL1347288 0.88 KDM4E (0.50) KDM4ERAB9AALDH1A1NPC1HPGD
Benzimidazole SCHEMBL29408372 0.85
Benzimidazole SCHEMBL6009 0.85
Benzimidazole SCHEMBL461969 0.85 SMN1; SMN2 (0.50) KDM4ERAB9AALDH1A1NPC1HPGD
Benzimidazole SCHEMBL29358377 0.85
Benzimidazole SCHEMBL10931770 0.85 SMN1; SMN2 (0.50) KDM4ERAB9AALDH1A1NPC1HPGD
SCHEMBL10817399 0.84 IP6K1 (0.59) TAAR1KDM4EMEN1KMT2ARAB9A
SCHEMBL14972936 0.84 IP6K1 (0.63) TAAR1KDM4EMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4572890-A Process for the production of images CIBA-GEIGY CORPORATION (US) 1986-02-25 US disclosed
US-4552604-A EPOXY RESINS, PHOTOPOLYMERIZATION, LAMINATION CIBA GEIGY CORPORATION (US) 1985-11-12 US disclosed
US-4500629-A Method of forming images from liquid masses CIBA-GEIGY CORPORATION (US) 1985-02-19 US disclosed
US-4252593-A Method of preparing reinforced composites CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed
US-3879356-A Light-sensitive polymeric compositions EASTMAN KODAK CO 1975-04-22 US disclosed