Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL10931770 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL29408372 | 1.00 | — | — | |
| Benzimidazole SCHEMBL29358377 | 1.00 | — | — | |
| Benzimidazole SCHEMBL6009 | 1.00 | — | — | |
| Benzimidazole SCHEMBL23673327 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL20531480 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL5131535 | 0.97 | — | — | |
| Benzimidazole SCHEMBL22551123 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 | |
| Benzimidazole SCHEMBL21046391 | 0.97 | — | — | |
| Benzimidazole SCHEMBL9589943 | 0.97 | SMN1; SMN2 (0.48) | SMN1; SMN2PDPK1CA12PARP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976153-B2 | Fluorinated polymerization catalysts and methods of making and using the same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2024-05-07 | — | — | US | claimed |
| US-20230374171-A1 | FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF HOUSTON SYSTEM | 2023-11-23 | — | — | US | claimed |
| EP-2173925-B1 | CORROSION PROTECTION OF BRONZES | MACDERMID ENTHONE INC (US) | 2020-09-16 | — | — | EP | claimed |
| CN-106467549-B | A kind of compound containing benzimidazole and its application on organic electroluminescence device | 江苏三月光电科技有限公司 | 2019-03-22 | — | — | CN | claimed |
| CN-106467548-B | A kind of compound containing benzimidazole and its application | 江苏三月光电科技有限公司 | 2019-03-05 | — | — | CN | claimed |
| CN-106467552-B | A kind of compound containing benzimidazole and its application in OLED device | 江苏三月光电科技有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-106467549-A | A kind of compound containing benzimidazole and its application on organic electroluminescence device | 江苏三月光电科技有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-106467548-A | A kind of compound containing benzimidazole and its application | 江苏三月光电科技有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-106467552-A | A kind of compound containing benzimidazole and its application in OLED | 江苏三月光电科技有限公司 | 2017-03-01 | — | — | CN | claimed |
| US-20100291303-A1 | ANTI-TARNISH COATINGS | ENTHONE INC. (US) | 2010-11-18 | — | — | US | claimed |
| EP-2246862-A1 | Organic electronic device comprising an organic semiconducting material | Novaled AG (DE) | 2010-11-03 | — | — | EP | claimed |
| US-20100151263-A1 | METALLIC SURFACE ENHANCEMENT | ENTHONE INC. (US) | 2010-06-17 | — | — | US | claimed |
| US-20240239923-A1 | FLUORINATED POLYMERIZATION CATALYSTS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF HOUSTON SYSTEM | 2024-07-18 | — | — | US | disclosed |
| CN-115838372-B | Triphenylethylene derivative and organic electroluminescent device comprising triphenylethylene derivative | 广东省大湾区华南理工大学聚集诱导发光高等研究院 | 2024-05-10 | — | — | CN | disclosed |
| US-11976153-B2 | Fluorinated polymerization catalysts and methods of making and using the same | UNIVERSITY OF HOUSTON SYSTEM (US) | 2024-05-07 | — | — | US | disclosed |
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
| EP-0196153-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-26 | — | — | EP | disclosed |
| US-4822880-A | 1,1'-SUBSTITUTED 2,2'-BIIMIDAZOLE OR BIBENZIMIDAZOLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-04-18 | — | — | US | disclosed |
| US-4696801-A | Process for the extraction of metal values with bisimidazole metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-29 | — | — | US | disclosed |
| EP-0196153-A2 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | PARG, PARN, NOP2 | SMN1; SMN2 1872/4885PDPK1 3377/4885CA12 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.