Methylene Chloride

Methylene Chloride

SCHEMBL10948817

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1.ClCCl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 1/20 0.50
ACHE P22303 4/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP2C19 P33261 1/20 0.41
MAPT P10636 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
CA2 P00918 2/20 0.36
IDO1 P14902 1/20 0.36
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
RAB9A P51151 1/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12240222 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL615437 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL76680 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL7486403 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL6123161 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL4893877 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL16982395 0.88 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CYP2C19
SCHEMBL5617928 0.85 ALDH1A1 (0.42) ALDH1A1TSHRACHETDP1CYP2C19
Hydrochloric Acid SCHEMBL25295730 0.85 ALDH1A1 (0.58) ALDH1A1TSHRACHETDP1CYP2C19
Ammonia Solution, Strong SCHEMBL8759606 0.85 ALDH1A1 (0.58) ALDH1A1TSHRACHETDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4552825-A Phosphorous diketonate electron accepting ring compounds as sensitizers for electron donating photoconductive compositions EASTMAN KODAK COMPANY (US) 1985-11-12 US disclosed
US-4496730-A Phosphorous diketonate electron accepting ring compounds as sensitizers for electron donating photoconductive compositions EASTMAN KODAK COMPANY (US) 1985-01-29 US disclosed
US-4365016-A ELECTROGRAPHY EASTMAN KODAK COMPANY (US) 1982-12-21 US disclosed