Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461958 | 0.85 | MEN1 (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9039351 | 0.81 | MEN1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL10946831 | 0.80 | TSHR (0.70) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL11187915 | 0.79 | MEN1 (0.57) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9066215 | 0.79 | RAB9A (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11229513 | 0.79 | MTOR (0.54) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL28429878 | 0.78 | MEN1 (0.60) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11643923 | 0.77 | CA12 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8830833 | 0.76 | KMT2A (0.79) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL357999 | 0.75 | MEN1 (0.71) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514419-A | Nematicidal use of hydrazinecarboxamides and carbothioamides | FMC CORPORATION (JP) | 1985-04-30 | — | — | US | claimed |
| US-4514419-A | Nematicidal use of hydrazinecarboxamides and carbothioamides | FMC CORPORATION (JP) | 1985-04-30 | — | — | US | disclosed |