Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10915151 | 0.85 | KMT2A (0.60) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL10913488 | 0.85 | KMT2A (0.60) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL10911236 | 0.84 | KMT2A (0.59) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10913625 | 0.84 | KMT2A (0.59) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL10911705 | 0.84 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10914663 | 0.83 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10914090 | 0.83 | KMT2A (0.58) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10911309 | 0.83 | CHEK1 (0.58) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| Oxalic Acid SCHEMBL10913836 | 0.83 | KMT2A (0.59) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL10914852 | 0.83 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |