⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205724 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL8542147 | 0.95 | — | — | |
| SCHEMBL5729641 | 0.67 | — | — | |
| SCHEMBL3219049 | 0.67 | — | — | |
| SCHEMBL5300456 | 0.67 | — | — | |
| SCHEMBL6922394 | 0.67 | — | — | |
| SCHEMBL2466217 | 0.65 | PDPK1 (0.32) | — | |
| SCHEMBL15907855 | 0.63 | — | — | |
| SCHEMBL11311220 | 0.62 | — | — | |
| SCHEMBL10572699 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153787-B2 | Azacytosine derivatives useful as antiviral agents | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-04-10 | — | — | US | disclosed |
| EP-1966226-B1 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | LEUVEN K U RES & DEV (BE) | 2010-11-10 | — | — | EP | disclosed |
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2009-01-01 | — | — | US | disclosed |
| EP-1966226-A2 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | K.U.Leuven Research & Development (BE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007065231-A2 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2007-06-14 | — | — | WO | disclosed |