⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205724 | 0.69 | — | — | |
| SCHEMBL1094925 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8542147 | 0.67 | — | — | |
| SCHEMBL14639314 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL30429172 | 0.65 | GPR84 (0.37) | — | |
| SCHEMBL11096389 | 0.64 | — | — | |
| SCHEMBL3219049 | 0.64 | — | — | |
| SCHEMBL5300456 | 0.64 | — | — | |
| SCHEMBL2466217 | 0.62 | PDPK1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL1430118 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363912-B1 | SUBSTITUTED IMIDAZOTRIAZINONES | BAYER HEALTHCARE AG (DE) | 2006-05-24 | — | — | EP | disclosed |
| US-6998402-B2 | Substituted imidazotriazinones | BAYER AKTIENGESELLSCHAFT (DE) | 2006-02-14 | — | — | US | disclosed |
| EP-1347978-B1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES AS PDE II-INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| US-20050009822-A1 | Novel substituted imidazotriazinones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | disclosed |
| EP-1363912-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES | Bayer Aktiengesellschaft (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1347978-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES AS PDE II-INHIBITORS | Bayer Aktiengesellschaft (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6573263-B2 | For improving perception, concentration power, learning power and/ or memory power | BAYER AKTIENGESELLSCHAFT (DE) | 2003-06-03 | — | — | US | disclosed |
| US-20020198377-A1 | Substituted imidazotriazinones | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-26 | — | — | US | disclosed |
| WO-2002068423-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-06 | — | — | WO | disclosed |
| WO-2002050078-A1 | NOVEL SUBSTITUTED IMIDAZOTRIAZINONES AS PDE II-INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-27 | — | — | WO | disclosed |