Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949964 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATHRATHRBGAA | |
| SCHEMBL10942288 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATHRATHRBGAA | |
| SCHEMBL10943626 | 0.99 | LMNA (0.39) | SMN1; SMN2LMNATHRATHRBGAA | |
| SCHEMBL1379797 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNATHRATHRBGAA | |
| SCHEMBL6273903 | 0.88 | LMNA (0.39) | SMN1; SMN2LMNATHRATHRBGAA | |
| SCHEMBL9719112 | 0.87 | PDE4A (0.41) | MAPTTXNRD1CTSB | |
| SCHEMBL9719246 | 0.87 | PDE4A (0.41) | MAPTTXNRD1CTSB | |
| SCHEMBL9719159 | 0.87 | PDE4A (0.41) | MAPTTXNRD1CTSB | |
| SCHEMBL9719167 | 0.87 | PDE4A (0.41) | MAPTTXNRD1CTSB | |
| SCHEMBL9719136 | 0.87 | PDE4A (0.41) | MAPTTXNRD1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554279-A | PLASMODICIDAL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1985-11-19 | — | — | US | disclosed |