Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952722 | 0.95 | MAPK1 (0.44) | MAPK1ALDH1A1GAATSHRUBE2N | |
| SCHEMBL10949738 | 0.76 | MAPK1 (0.39) | MAPK1ALDH1A1GAAPOLBALOX15 | |
| SCHEMBL10954844 | 0.73 | MAPK1 (0.39) | MAPK1ALDH1A1GAAPOLBALOX15 | |
| SCHEMBL10951025 | 0.70 | TSHR (0.45) | ALDH1A1GAATSHRMEN1KMT2A | |
| SCHEMBL6485138 | 0.70 | PTGES (0.58) | ALDH1A1PDE3BPDE3APOLBHPGD | |
| SCHEMBL6483250 | 0.70 | PTGES (0.58) | ALDH1A1PDE3BPDE3APOLBHPGD | |
| SCHEMBL6478277 | 0.69 | CHRNA7 (0.55) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL6487769 | 0.69 | CHRNA7 (0.55) | ALDH1A1PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL10957000 | 0.68 | KMT2A (0.45) | MAPK1ALDH1A1GAAPOLBMEN1 | |
| SCHEMBL34474846 | 0.68 | CYP2D6 (0.39) | MAPK1ALDH1A1GAAPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4494547-A | 2H-isoindolediones, their synthesis and use as radiosensitizers | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 1985-01-22 | — | — | US | disclosed |