Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767113 | 0.87 | ALDH1A1 (0.46) | MAPTRAB9ATDP1MEN1KMT2A | |
| SCHEMBL5692745 | 0.81 | ALDH1A1 (0.50) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL31558904 | 0.77 | MAPT (0.64) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL18826528 | 0.76 | ALDH1A1 (0.41) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11329248 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11329238 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11318226 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL16556 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL205992 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 | |
| SCHEMBL11329226 | 0.75 | MAPT (1.00) | MAPTRAB9ANPC1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496482-A | FROM ISOCYANATOSILANES, FOR BONDING TO SUBSTRATES | UNION CARBIDE CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| US-4316041-A | BOND TO GLASS | UNION CARBIDE CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |