Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208792 | 1.00 | MAPT (0.64) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL10950289 | 1.00 | MAPT (0.64) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL6244793 | 0.84 | ALDH1A1 (0.61) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL22462223 | 0.82 | MAPT (0.66) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL30668590 | 0.82 | MAPT (0.66) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL14305290 | 0.81 | MAPT (0.61) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL22478745 | 0.81 | MAPT (0.61) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL11334868 | 0.81 | MAPT (0.69) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL19787945 | 0.81 | MAPT (0.64) | MAPTNPC1PKMRAB9AKDM4E | |
| SCHEMBL11334864 | 0.81 | MAPT (0.69) | MAPTNPC1PKMRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4511655-A | HYDROLYSIS WITH MICROORGANISM OR ENZYME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-04-16 | — | — | US | disclosed |