Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949873 | 1.00 | TDP1 (0.38) | TDP1HDAC1CNR2CACNA1FCHRM2 | |
| SCHEMBL9342079 | 0.89 | HDAC1 (0.46) | TDP1HDAC1CNR2CACNA1FCHRM2 | |
| SCHEMBL10950919 | 0.86 | HDAC1 (0.37) | TDP1HDAC1CNR2GAAMAPT | |
| SCHEMBL10947652 | 0.85 | HDAC1 (0.37) | TDP1HDAC1CNR2PDE4BEPHX1 | |
| SCHEMBL10947478 | 0.84 | HDAC1 (0.39) | TDP1HDAC1CNR2CACNA1FCHRM2 | |
| SCHEMBL9333232 | 0.84 | NPC1 (0.43) | TDP1HDAC1PDE4BGAAMAPT | |
| SCHEMBL10950115 | 0.84 | HDAC1 (0.38) | TDP1HDAC1CNR2CACNA1FCHRM2 | |
| SCHEMBL10948149 | 0.82 | MAPT (0.46) | TDP1HDAC1PDE4BGAAMAPT | |
| SCHEMBL10953536 | 0.81 | CYTH2 (0.43) | CNR2GAAMAPTPOLBALDH1A1 | |
| SCHEMBL10956865 | 0.78 | HDAC1 (0.37) | TDP1HDAC1CNR2PDE4BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069585-B1 | COLOR-FORMING SULFONAMIDODIPHENYLAMINES, PHOTOGRAPHIC ELEMENTS CONTAINING THEM AND CORRESPONDING SULFONIMIDE DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4499304-A | COLOR PHOTOGRAPHY;SILVER HALIDE EMULSIONS; PRINTING PLATES; IMAGES | EASTMAN KODAK COMPANY (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0069585-A1 | Color-forming sulfonamidodiphenylamines, photographic elements containing them and corresponding sulfonimide dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-01-12 | — | — | EP | disclosed |