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Sugi Predict / Targets / CYTH2

CYTH2

Cytohesin-2 · Q99418 · CYTH2 on Sugi Atlas →

2,258 patent compounds predicted against CYTH2, 1,555 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL7178299 SCHEMBL7178299 0.73 4/20
SCHEMBL1128401 SCHEMBL1128401 0.63 4/20
SCHEMBL7129901 SCHEMBL7129901 0.44 4/20
Sulfuric Acid Sulfuric Acid (SCHEMBL7128216) 0.41 4/20
SCHEMBL812686 SCHEMBL812686 0.74 3/20
SCHEMBL8661428 SCHEMBL8661428 0.54 3/20
SCHEMBL8656948 SCHEMBL8656948 0.50 3/20
SCHEMBL8660475 SCHEMBL8660475 0.50 3/20
SCHEMBL743630 SCHEMBL743630 0.42 3/20
SCHEMBL1577057 SCHEMBL1577057 0.42 3/20
SCHEMBL3909224 SCHEMBL3909224 0.41 3/20
SCHEMBL3950097 SCHEMBL3950097 0.41 3/20
SCHEMBL8018706 SCHEMBL8018706 0.41 3/20
Sulfuric Acid Sulfuric Acid (SCHEMBL3336768) 0.40 3/20
SCHEMBL2436550 SCHEMBL2436550 0.70 2/20
SCHEMBL7176831 SCHEMBL7176831 0.70 2/20
SCHEMBL3267594 SCHEMBL3267594 0.69 2/20
SCHEMBL5822638 SCHEMBL5822638 0.68 2/20
SCHEMBL7180209 SCHEMBL7180209 0.67 2/20
Acetic Acid Acetic Acid (SCHEMBL3426591) 0.66 2/20

Clinical trials — most relevant to CYTH2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomas PHASE2COMPLETED
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 PHASE1/PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*) PHASE1RECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Observational Study of Blood Treated With Cytolin nanCOMPLETED
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
The Mechanistic Biology of Primary Immunodeficiency Disorders nanRECRUITING
Chromosome 5Q Gene Variants and Asthma-Related Traits nanCOMPLETED
NCF Gene & TNFSF4 in SLE Patients nanUNKNOWN
Study of Usher Syndromes, Type 1 and Type 2 nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Family Blood Pressure Program - SAPPHIRe Network nanCOMPLETED
Family Blood Pressure Program - GENOA nanCOMPLETED
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
Genetic Variants Associated With Adolescent Suicide Attempts nanCOMPLETED
Childhood-Onset Essential Hypertension Natural History Study nanRECRUITING
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Inflammatory Genomics in Human Carotid Artery Disease nanCOMPLETED
The Etiology and Progression of Brain Tumors nanCOMPLETED
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease nanCOMPLETED
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a CYTH2 binder may also engage these)

ProteinNameSimilarity
P63035 — 1.000 P63035 →
P63034 — 1.000 P63034 →
Q76MY7 — 1.000 Q76MY7 →
P97696 — 1.000 P97696 →
O08967 — 0.999 O08967 →
Q80YW0 — 0.997 Q80YW0 →
Q2KI41 — 0.995 Q2KI41 →
Q76MZ1 — 0.993 Q76MZ1 →
CYTH3 Cytohesin-3 0.992 landscape →
Q9QX11 — 0.992 Q9QX11 →
Q9UIA0 — 0.991 Q9UIA0 →
Q15438 — 0.991 Q15438 →
P97694 — 0.990 P97694 →
P52735 — 0.976 P52735 →
Q4KWH8 — 0.973 Q4KWH8 →
Q9Y6D5 — 0.973 Q9Y6D5 →
Q60992 — 0.973 Q60992 →
Q66K14 — 0.971 Q66K14 →
ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 0.971 landscape →
P51432 — 0.971 P51432 →
Q92503 — 0.971 Q92503 →
P26675 — 0.970 P26675 →
Q8K394 — 0.970 Q8K394 →
B4F7E7 — 0.969 B4F7E7 →
Q5SVR0 — 0.969 Q5SVR0 →
Q91ZT5 — 0.969 Q91ZT5 →
Q62688 — 0.969 Q62688 →
Q4KWH5 — 0.969 Q4KWH5 →
Q86T65 — 0.968 Q86T65 →
RAPGEF4 Rap guanine nucleotide exchange factor 4 0.968 landscape →