Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.88 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.63 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600037 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL5864236 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL5863714 | 0.90 | POLB (0.93) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL17335877 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL6224747 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL1042778 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL3862351 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL11615671 | 0.90 | POLB (0.93) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL21799935 | 0.90 | HRH3 (0.72) | HRH3POLBHDAC1CXCR4CXCL12 | |
| SCHEMBL24574127 | 0.89 | HRH3 (0.71) | HRH3POLBHDAC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003809-A1 | ANTITUMOUR COMPOUNDS | PHARMA MAR, S.A. (ES) | 2008-01-10 | — | — | WO | disclosed |
| US-4507465-A | IMPACT STRENGTH | TORAY INDUSTRIES, INC. (JP) | 1985-03-26 | — | — | US | disclosed |
| EP-0113252-A2 | Process for producing block copolyamide | TORAY INDUSTRIES, INC. (JP) | 1984-07-11 | — | — | EP | disclosed |