Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.93 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.54 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863714 | 1.00 | POLB (0.93) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL11112228 | 0.98 | POLB (0.96) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL8809145 | 0.95 | POLB (0.83) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL31083251 | 0.94 | POLB (0.89) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL8808145 | 0.90 | POLB (0.76) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL3236686 | 0.90 | POLB (0.81) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL10953965 | 0.90 | HRH3 (0.88) | POLBHRH3MEN1KMT2AHDAC1 | |
| SCHEMBL19329149 | 0.82 | POLB (0.70) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL7318100 | 0.81 | POLB (0.69) | POLBHRH3LMNAALOX12EPHX1 | |
| SCHEMBL3359770 | 0.81 | POLB (0.69) | POLBHRH3LMNAALOX12EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127673-A | Combating fungi with new N-4-halobenzyl-N-cycloalkyl-N'-phenylureas and thioureas | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1978-11-28 | — | — | US | disclosed |