Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 1.00 |
| ▸ | DAO | P14920 | 1/20 | 1.00 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 1.00 |
| ▸ | CES2 | O00748 | 3/20 | 0.78 |
| ▸ | CES1 | P23141 | 3/20 | 0.78 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA5A | P35218 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4591761 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9751726 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL975929 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11602198 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 1.00 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3614991-A1 | REDUCING THE TURBIDITY OF NAIL VARNISH | International Lacquers S.A. (LU) | 2020-03-04 | — | — | EP | claimed |
| WO-2018197566-A1 | REDUCING THE TURBIDITY OF NAIL VARNISH | INTERNATIONAL LACQUERS S.A. (LU) | 2018-11-01 | — | — | WO | claimed |
| EP-0354323-A2 | Antidiabetic phosphates | AMERICAN CYANAMID COMPANY (US) | 1990-02-14 | — | — | EP | claimed |
| US-10711164-B2 | Pressure-sensitive adhesive comprising a polymer component and a saccharide component and method for bonding a first substrate to a second substrate with same | TESA SE (DE) | 2020-07-14 | — | — | US | disclosed |
| EP-3614991-A1 | REDUCING THE TURBIDITY OF NAIL VARNISH | International Lacquers S.A. (LU) | 2020-03-04 | — | — | EP | disclosed |
| US-20180362812-A1 | METHOD FOR PRODUCING COLORLESS AND AGING-RESISTANT, POLYACRYLATE-BASED PRESSURE-SENSITIVE ADHESIVE COMPOUNDS | TESA SE (DE) | 2018-12-20 | — | — | US | disclosed |
| WO-2018197566-A1 | REDUCING THE TURBIDITY OF NAIL VARNISH | INTERNATIONAL LACQUERS S.A. (LU) | 2018-11-01 | — | — | WO | disclosed |
| EP-2086915-B1 | TRITYL CHLORIDE RECOVERY | TATE & LYLE TECHNOLOGY LTD (GB) | 2015-04-29 | — | — | EP | disclosed |
| US-8153849-B2 | Triarylmethylating sucrose in presence of amine to form 6,1',6'-tri-O-triarylmethylsucrose and byproducts, acylating to form 6,1',6'-tri-O-triarylmethylsucrose pentaester, separating, washing with hydrogen halide to remove amine | TATE & LYLE TECHNOLOGY LTD. (GB) | 2012-04-10 | — | — | US | disclosed |
| EP-2086915-A2 | TRITYL CHLORIDE RECOVERY | Tate & Lyle Technology Limited (GB) | 2009-08-12 | — | — | EP | disclosed |
| US-20080234526-A1 | Triarylmethylating sucrose in presence of amine to form 6,1',6'-tri-O-triarylmethylsucrose and byproducts, acylating to form 6,1',6'-tri-O-triarylmethylsucrose pentaester, separating, washing with hydrogen halide to remove amine | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2008-09-25 | — | — | US | disclosed |
| WO-1994000477-A1 | SUBSTITUTED LACTOSE DERIVATIVES AS CELL ADHESION INHIBITORS | GLYCOMED INCORPORATED (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993010796-A1 | SUBSTITUTED LACTOSE AND LACTOSAMINE DERIVATIVES AS CELL ADHESION INHIBITORS | GLYCOMED, INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| US-4968790-A | HYPOGLYCEMIC AGENTS, PLANT GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| US-4943629-A | HYPOGLYCEMIC AGENTS; ENZYME STIMULATORS, INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0354323-A2 | Antidiabetic phosphates | AMERICAN CYANAMID COMPANY (US) | 1990-02-14 | — | — | EP | disclosed |
| EP-0354322-A2 | Antidiabetic alpha-substituted phosphonates | AMERICAN CYANAMID COMPANY (US) | 1990-02-14 | — | — | EP | disclosed |
| US-4442123-A | 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1984-04-10 | — | — | US | disclosed |
| EP-0015652-A1 | 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1980-09-17 | — | — | EP | disclosed |
| US-3936393-A | 2-METHOXY-4-CINNAMYL PHENOL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-02-03 | — | — | US | disclosed |