Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471759 | 0.86 | MAPT (0.77) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL2003074 | 0.86 | MAPT (0.77) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL7566765 | 0.86 | MAPT (0.77) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL13389060 | 0.86 | MAPT (0.77) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL10953379 | 0.85 | HDAC1 (0.62) | MEN1KMT2AMAPTHTTGAA | |
| SCHEMBL13776958 | 0.84 | HDAC2 (0.59) | MEN1KMT2AATMMAPTHTT | |
| SCHEMBL10954317 | 0.84 | KMT2A (0.71) | MEN1KMT2ACA1CA2MAPT | |
| SCHEMBL12345556 | 0.83 | MEN1 (0.67) | MEN1KMT2AATMMAPTHTT | |
| SCHEMBL1565360 | 0.82 | SELL (0.66) | MEN1KMT2AFFAR1 | |
| SCHEMBL27160281 | 0.82 | NPY5R (0.77) | MEN1KMT2AMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |