SCHEMBL7566765

SCHEMBL7566765

O=C(CCc1ccc(C(=O)O)cc1)Nc1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.77
HTT P42858 1/20 0.77
GAA P10253 3/20 0.69
LMNA P02545 1/20 0.62
NPY5R Q15761 1/20 0.61
HDAC1 Q13547 3/20 0.60
HDAC3 O15379 2/20 0.60
HDAC4 P56524 2/20 0.60
HDAC7 Q8WUI4 2/20 0.60
HDAC2 Q92769 2/20 0.60
HDAC10 Q969S8 2/20 0.60
HDAC11 Q96DB2 2/20 0.60
HDAC8 Q9BY41 2/20 0.60
HDAC6 Q9UBN7 2/20 0.60
HDAC9 Q9UKV0 2/20 0.60
HDAC5 Q9UQL6 2/20 0.60
KMT2A Q03164 4/20 0.58
ALDH1A1 P00352 2/20 0.58
RAB9A P51151 1/20 0.57
TSHR P16473 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2003074 0.93 MAPT (0.77) MAPTHTTGAALMNANPY5R
SCHEMBL3061430 0.88 MAPT (1.00) MAPTHTTGAALMNAHDAC1
Hydrochloric Acid SCHEMBL27689202 0.86 MAPT (0.96) MAPTHTTGAALMNAHDAC1
SCHEMBL10953379 0.86 HDAC1 (0.62) MAPTHTTGAANPY5RHDAC1
SCHEMBL10954256 0.86 MEN1 (0.59) MAPTHTTGAANPY5RHDAC1
SCHEMBL12915848 0.85 MAPT (0.80) MAPTHTTGAALMNAHDAC1
Methyl Alcohol SCHEMBL4593446 0.84 MAPT (0.93) MAPTHTTGAALMNAHDAC1
SCHEMBL1996378 0.84 HCAR2 (0.60) MAPTHTTGAANPY5RHDAC1
SCHEMBL1996813 0.84 TRPV1 (0.75) MAPTHTTGAAHDAC1HDAC3
SCHEMBL5902414 0.83 MAPT (0.77) MAPTHTTGAALMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020124329-A1 HAIR COLOURING COMPOSITIONS AND THEIR USE PRATT DOMINIC (GB) 2002-09-12 US disclosed
EP-1003466-A4 HAIR COLOURING COMPOSITIONS AND THEIR USE PROCTER & GAMBLE (US) 2001-01-03 EP disclosed
EP-1003466-A1 HAIR COLOURING COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 2000-05-31 EP disclosed
WO-1998052523-A1 HAIR COLOURING COMPOSITIONS AND THEIR USE THE PROCTER & GAMBLE COMPANY (US) 1998-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020124329-A1 HAIR COLOURING COMPOSITIONS AND THEIR USE TYR, DEK, DAO MAPT 3299/4885HTT 3588/4885GAA 3427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.