Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.51 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846410 | 1.00 | KDM5A (0.51) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10954525 | 1.00 | KDM5A (0.51) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL11196822 | 0.93 | GPR84 (0.59) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL11196799 | 0.93 | GPR84 (0.59) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10953905 | 0.93 | MAPT (0.58) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10849849 | 0.93 | GPR84 (0.59) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10953909 | 0.93 | MAPT (0.58) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10844626 | 0.93 | MAPT (0.58) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL11203743 | 0.93 | GPR84 (0.59) | KDM5AKDM4CPHF8KDM2AKDM7A | |
| SCHEMBL10845618 | 0.93 | GPR84 (0.59) | KDM5AKDM4CPHF8KDM2AKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087032-B1 | BICYCLOHEXYL DERIVATIVES HAVING LIQUID-CRYSTAL PROPERTIES | MERCK PATENT GmbH (DE) | 1985-05-08 | — | — | EP | disclosed |
| EP-0087032-A1 | Bicyclohexyl derivatives having liquid-crystal properties | MERCK PATENT GmbH (DE) | 1983-08-31 | — | — | EP | disclosed |