Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.59 |
| ▸ | REN | P00797 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955254 | 1.00 | ACE (0.59) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10733063 | 0.95 | ACE (0.64) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10953051 | 0.95 | ACE (0.64) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10954483 | 0.93 | ACE (0.56) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10954475 | 0.93 | ACE (0.56) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10657795 | 0.90 | ACE (0.59) | ACERENLMNAKDM4EF2 | |
| SCHEMBL11014497 | 0.87 | ACE (0.49) | ACERENLMNAKDM4EF2 | |
| SCHEMBL10734607 | 0.86 | REN (0.66) | ACERENLMNAKDM4EF2 | |
| SCHEMBL24580459 | 0.84 | ACE (0.54) | ACERENLMNAKDM4EF2 | |
| SCHEMBL11378678 | 0.83 | PREP (0.57) | ACERENLMNAKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554100-A | ENZYME INHIBITORS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1985-11-19 | — | — | US | disclosed |