Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CBFB | Q13951 | 5/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955417 | 0.88 | TDP1 (0.41) | TDP1CBFBNPSR1POLBALDH1A1 | |
| SCHEMBL10955143 | 0.85 | RAD52 (0.47) | TDP1RAD52UBE2NKMT2APOLB | |
| SCHEMBL5029790 | 0.79 | KDM4E (0.62) | TDP1CBFBRAD52UBE2NNPSR1 | |
| SCHEMBL3301287 | 0.78 | ALDH1A1 (0.51) | TDP1KMT2APOLBALDH1A1RAB9A | |
| SCHEMBL10578208 | 0.78 | KMT2A (0.55) | TDP1RAD52UBE2NKMT2APOLB | |
| SCHEMBL15947594 | 0.76 | TDP1 (0.61) | TDP1CBFBRAD52UBE2NNPSR1 | |
| SCHEMBL10957386 | 0.76 | RAD52 (0.48) | TDP1RAD52UBE2NKMT2APOLB | |
| SCHEMBL24553578 | 0.76 | TDP1 (0.49) | TDP1CBFBRAD52UBE2NNPSR1 | |
| SCHEMBL4226862 | 0.76 | ALDH1A1 (0.56) | TDP1CBFBKMT2APOLBALDH1A1 | |
| SCHEMBL10958816 | 0.74 | ALDH1A1 (0.41) | RAD52UBE2NKMT2APOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550118-A | ANTIULCER, ANTISECRETORY AGENT, HISTAMINE ANTAGONIST | IKEDA MOHANDO CO., LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0111685-A1 | Benzazoles as histamine H2 receptor antagonists | Ikeda Mohando Co., Ltd. (JP) | 1984-06-27 | — | — | EP | disclosed |