Fluoride

Fluoride

SCHEMBL10956643

F.O=C(O)Nc1cccc(Cl)c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
LMNA P02545 2/20 0.71
MAPT P10636 2/20 0.71
HTT P42858 2/20 0.71
ALDH1A1 P00352 2/20 0.71
RAB9A P51151 4/20 0.70
NPC1 O15118 3/20 0.70
KCNK3 O14649 1/20 0.57
KCNK9 Q9NPC2 1/20 0.57
HTR3E A5X5Y0 1/20 0.57
HTR3B O95264 1/20 0.57
HTR3A P46098 1/20 0.57
HTR3D Q70Z44 1/20 0.57
HTR3C Q8WXA8 1/20 0.57
EGFR P00533 1/20 0.57
MMP1 P03956 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57
MAOA P21397 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1884170 0.98 MEN1 (0.74) MEN1KMT2ALMNAMAPTHTT
Fumaric Acid SCHEMBL27519308 0.89 MEN1 (0.62) MEN1KMT2ALMNAMAPTHTT
SCHEMBL2682054 0.83 KMT2A (1.00) MEN1KMT2ALMNAMAPTHTT
SCHEMBL11858223 0.83 GPR35 (0.67) MEN1KMT2AMAPTKCNK3KCNK9
SCHEMBL10344695 0.82 MEN1 (1.00) MEN1KMT2ALMNAMAPTHTT
SCHEMBL10884791 0.82 GPR35 (0.74) MEN1KMT2ALMNAMAPTHTT
SCHEMBL29533340 0.82 MEN1 (1.00) MEN1KMT2ALMNAMAPTHTT
SCHEMBL4638783 0.82 MEN1 (0.73) MEN1KMT2ALMNAMAPTHTT
SCHEMBL2094553 0.82 MEN1 (0.74) MEN1KMT2ALMNAMAPTHTT
SCHEMBL11066912 0.82 MEN1 (0.74) MEN1KMT2ALMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4515812-A Combating fungi with N-sulphenylated ureas BAYER AKTIENGESELLSCHAFT (DE) 1985-05-07 US disclosed
US-4397869-A Combating fungi with N-sulphenylated ureas BAYER AKTIENGESELLSCHAFT (DE) 1983-08-09 US disclosed