Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958256 | 1.00 | KDM4E (0.52) | KDM4ERECQLALDH1A1HPGDALOX15 | |
| SCHEMBL10954549 | 0.93 | RECQL (0.58) | KDM4ERECQLALDH1A1HPGDALOX15 | |
| SCHEMBL10954555 | 0.93 | RECQL (0.58) | KDM4ERECQLALDH1A1HPGDALOX15 | |
| SCHEMBL10956460 | 0.91 | FDPS (0.50) | CYSLTR2CYSLTR1LMNACYP1A2MAPT | |
| SCHEMBL10956451 | 0.91 | FDPS (0.50) | CYSLTR2CYSLTR1LMNACYP1A2MAPT | |
| SCHEMBL5035745 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL5035751 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1HPGDALOX15MAPK1 | |
| SCHEMBL10955363 | 0.85 | FDPS (0.48) | RECQLCYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL10955362 | 0.85 | FDPS (0.48) | RECQLCYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL11041707 | 0.84 | PPARG (0.62) | CYSLTR2CYSLTR1LMNACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083228-B1 | PHARMACEUTICALLY ACTIVE PHENYLCARBOXYLIC ACID DERIVATIVES | ICI AMERICAS INC. (US) | 1985-05-15 | — | — | EP | claimed |
| EP-0083228-A1 | Pharmaceutically active phenylcarboxylic acid derivatives | ICI AMERICAS INC. (US) | 1983-07-06 | — | — | EP | claimed |
| EP-0083228-B1 | PHARMACEUTICALLY ACTIVE PHENYLCARBOXYLIC ACID DERIVATIVES | ICI AMERICAS INC. (US) | 1985-05-15 | — | — | EP | disclosed |
| US-4499299-A | Pharmaceutically active phenylcarboxylic acid derivatives | ICI AMERICAS INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0083228-A1 | Pharmaceutically active phenylcarboxylic acid derivatives | ICI AMERICAS INC. (US) | 1983-07-06 | — | — | EP | disclosed |