Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753592 | 0.90 | MAPT (0.63) | MAPTADORA3HDAC3HDAC4HDAC1 | |
| SCHEMBL10948598 | 0.89 | MAPT (0.62) | MAPTADORA3HDAC3HDAC4HDAC1 | |
| SCHEMBL2901438 | 0.83 | NR3C1 (0.60) | MAPTADORA3HDAC3HDAC4HDAC1 | |
| SCHEMBL2020280 | 0.82 | ABL1 (0.73) | MAPTADORA3GSTO1ALDH1A1RAB9A | |
| SCHEMBL22753366 | 0.82 | ROCK1 (0.70) | MAPTADORA3GSTO1ALDH1A1RAB9A | |
| SCHEMBL10921715 | 0.82 | MAPT (0.72) | MAPTADORA3GSTO1ALDH1A1RAB9A | |
| SCHEMBL3823589 | 0.82 | MAPT (0.72) | MAPTADORA3GSTO1ALDH1A1RAB9A | |
| SCHEMBL10813540 | 0.82 | MAPT (0.88) | MAPTADORA3GSTO1ALDH1A1RAB9A | |
| SCHEMBL1621409 | 0.81 | MAPT (0.56) | MAPTADORA3HDAC3HDAC4HDAC1 | |
| SCHEMBL22753373 | 0.81 | MAPT (0.68) | MAPTHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501750-A | ANTIARTHRITIC AGENTS | Mitsui Toatsu Kaguku Kabushiki Kaisha (JP) | 1985-02-26 | — | — | US | disclosed |
| EP-0069154-A1 | NOVEL THIAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND MEDICINAL COMPOSITION CONTAINING SAME | MITSUI TOATSU KAGAKU KABUSHIKI KAISHA (JP) | 1983-01-12 | — | — | EP | disclosed |