Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | OGG1 | O15527 | 1/20 | 0.53 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11356340 | 0.85 | OGG1 (0.57) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL11372412 | 0.85 | OGG1 (0.60) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL10955545 | 0.85 | OGG1 (0.53) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL10874250 | 0.84 | OGG1 (0.58) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL11191705 | 0.83 | OGG1 (0.55) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL8757402 | 0.82 | OGG1 (0.58) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL10874515 | 0.81 | OGG1 (0.53) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL10917880 | 0.81 | OGG1 (0.61) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL9665470 | 0.81 | OGG1 (0.61) | CYP3A4OGG1CYP27B1PDCD1CD274 | |
| SCHEMBL10916395 | 0.81 | OGG1 (0.61) | CYP3A4OGG1CYP27B1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57140768-A | — | — | None | — | — | JP | disclosed |
| EP-0054974-B1 | IMIDAZOLYLPROPANOL COMPOUNDS AND THEIR ACID ADDITION SALTS, AND PRODUCTION AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-07-10 | — | — | EP | disclosed |
| JP-S57140768-A | IMIDAZOLYLPROPANOL DERIVATIVE | SUMITOMO CHEM CO LTD | 1982-08-31 | — | — | JP | disclosed |
| EP-0054974-A1 | Imidazolylpropanol compounds and their acid addition salts, and production and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-30 | — | — | EP | disclosed |