SCHEMBL10959083

SCHEMBL10959083

CC(NC(=O)O)(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.43
ACP3 P15309 1/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 2/20 0.42
SSTR4 P31391 3/20 0.41
PPARG P37231 2/20 0.40
PPARA Q07869 2/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
TACR3 P29371 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PLK1 P53350 1/20 0.39
HPGD P15428 3/20 0.38
CYP2C19 P33261 4/20 0.38
CYP3A4 P08684 2/20 0.38
TSHR P16473 1/20 0.38
HDAC3 O15379 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566692 0.82 SSTR4 (0.52) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL28905042 0.79 HDAC3 (0.50) KDM4EALDH1A1SSTR4KMT2ACYP2C19
SCHEMBL10708482 0.76 KDM4E (0.49) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL27347246 0.73 KMT2A (0.49) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL503390 0.73 KDM4E (0.46) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL4678773 0.73 KDM4E (0.53) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL7287554 0.73 KDM4E (0.53) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL4592424 0.73 KDM4E (0.53) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL19130800 0.73 CYP2C19 (0.56) KIF11ACP3KDM4EALDH1A1HSD17B10
SCHEMBL9806370 0.73 CYP2C19 (0.56) KIF11ACP3KDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4497887-A Thermal development type diazo copying material with hydrophobic resin encapsulated coupler particle Ricoh Compay, Ltd. (JP) 1985-02-05 US disclosed