Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592424 | 0.91 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL27347246 | 0.87 | KMT2A (0.49) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL4592642 | 0.81 | CYP2C9 (0.52) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL7287554 | 0.80 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL4678773 | 0.80 | KDM4E (0.53) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL503390 | 0.80 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL599245 | 0.79 | PPARG (0.52) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL8580845 | 0.79 | ACP3 (0.44) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL668729 | 0.79 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1PPARGPPARA | |
| SCHEMBL11601001 | 0.79 | KIF11 (0.48) | KDM4EHSD17B10ALDH1A1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179487-B1 | 2-PHENYLPROPIONIC ACID ESTERS, METHOD FOR OPTICAL RESOLUTION THEREOF AND OPTICALLY ACTIVE SUBSTANCE THEREOF | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |