Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000490 | 1.00 | PRSS1 (0.49) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL10953513 | 0.90 | PRSS1 (0.54) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL10953509 | 0.90 | PRSS1 (0.54) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL7692366 | 0.87 | KMT2A (0.48) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL10783888 | 0.86 | ALDH1A1 (0.49) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL5150201 | 0.86 | AKT1 (0.45) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL10783884 | 0.86 | ALDH1A1 (0.49) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL4961740 | 0.86 | AKT1 (0.45) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL20563855 | 0.84 | AKT1 (0.50) | PRSS1PRSS2PRSS3AKT1KMT2A | |
| SCHEMBL10701813 | 0.84 | ELANE (0.45) | PRSS1PRSS2PRSS3AKT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491326-C | 3-hydroxy olefine acid derivative and its preparation and application | CHINESE ACAD INST CHEMISTRY (CN) | 2009-05-27 | — | — | CN | disclosed |
| CN-101020639-A | 3-hydroxy olefine acid derivative and its prepn and application | CHINESE ACAD INST CHEMISTRY (CN) | 2007-08-22 | — | — | CN | disclosed |
| US-4537724-A | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |