Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807038 | 0.83 | BACE1 (0.33) | BACE1TRPA1 | |
| SCHEMBL27930103 | 0.81 | BACE1 (0.35) | BACE1TRPA1 | |
| SCHEMBL27662416 | 0.81 | BACE1 (0.35) | BACE1TRPA1 | |
| SCHEMBL28001724 | 0.79 | BACE1 (0.31) | BACE1 | |
| SCHEMBL27930647 | 0.79 | BACE1 (0.31) | BACE1 | |
| SCHEMBL28206346 | 0.79 | BACE1 (0.31) | BACE1 | |
| SCHEMBL27423963 | 0.78 | BACE1 (0.30) | BACE1 | |
| SCHEMBL28110668 | 0.78 | BACE1 (0.30) | BACE1 | |
| SCHEMBL27548732 | 0.72 | MMP2 (0.31) | — | |
| SCHEMBL28461077 | 0.71 | BACE1 (0.33) | BACE1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136893-A2 | Benzo[a]phenothiazines and hydro-derivatives and pharmaceutical compositions containing them | MERCK FROSST CANADA INC. (CA) | 1985-04-10 | — | — | EP | claimed |