Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594309 | 1.00 | ACE (0.52) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9731770 | 0.99 | ACE (0.51) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9698092 | 0.98 | ACE (0.52) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9731915 | 0.98 | ACE (0.52) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL9698089 | 0.98 | ACE (0.52) | ACEMEN1KMT2AUSP2LMNA | |
| Trifluoroacetic Acid SCHEMBL9247888 | 0.94 | ACE (0.47) | ACEMEN1KMT2AUSP2LMNA | |
| Trifluoroacetic Acid SCHEMBL9773139 | 0.92 | ACE (0.47) | ACEMEN1KMT2AUSP2LMNA | |
| Trifluoroacetic Acid SCHEMBL9592921 | 0.92 | ACE (0.47) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL14370435 | 0.91 | ACE (0.54) | ACEMEN1KMT2AUSP2LMNA | |
| SCHEMBL13609888 | 0.85 | FKBP1A (0.51) | ACEMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525301-A | REACTING TRIFLUOROMETHANE SULFONIC ACID DERIVATIVES WITH AMINO ACID ESTERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-06-25 | — | — | US | disclosed |