Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3340184 | 0.66 | CRBN (0.39) | CRBNDDB1GAA | |
| SCHEMBL19370324 | 0.60 | CRBN (0.38) | CRBNDDB1GAA | |
| SCHEMBL3182138 | 0.60 | — | — | |
| SCHEMBL18019315 | 0.60 | — | — | |
| SCHEMBL7746034 | 0.60 | — | — | |
| SCHEMBL1586116 | 0.60 | — | — | |
| SCHEMBL20329604 | 0.60 | — | — | |
| SCHEMBL11568357 | 0.58 | CRBN (0.55) | CRBNDDB1GAA | |
| Succinimide SCHEMBL20640078 | 0.58 | — | — | |
| SCHEMBL23121074 | 0.57 | CRBN (0.56) | CRBNDDB1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59013780-A | — | — | None | — | — | JP | disclosed |
| EP-0099091-B1 | HEXAHYDRODIOXOPYRIMIDINES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-10-29 | — | — | EP | disclosed |
| US-4536504-A | ANTITUMOR, ANTIVIRAL, AND ANTIBACTERIAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |
| JP-S5913780-A | FLUOROURACIL DERIVATIVE AND ANTITUMOR AGENT | TAKEDA CHEM IND LTD | 1984-01-24 | — | — | JP | disclosed |