Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963903 | 0.94 | ESRRA (0.45) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL8656155 | 0.85 | ESRRA (0.47) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10962597 | 0.84 | ESRRA (0.47) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10967979 | 0.84 | IDO1 (0.46) | ESRRANPC1RAB9ACYP1A2LMNA | |
| SCHEMBL10962421 | 0.83 | ESRRA (0.45) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL8656968 | 0.82 | ESRRA (0.43) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10991633 | 0.80 | LMNA (0.44) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10963006 | 0.79 | MAPT (0.50) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10962726 | 0.77 | ESRRA (0.49) | ESRRATSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL10965973 | 0.77 | ESRRA (0.46) | ESRRATSHRNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050321-B1 | NOVEL BICYCLOOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND PESTICIDES CONTAINING THEM | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |