Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024815 | 0.76 | KDM4E (0.41) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL10963504 | 0.71 | CYP1A2 (0.38) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL6699250 | 0.66 | NPC1 (0.43) | CYP1A2CYP3A4KMT2ANPSR1MEN1 | |
| SCHEMBL29812111 | 0.66 | POLB (0.38) | CYP1A2CYP3A4BRD4HSD17B10KMT2A | |
| SCHEMBL4613962 | 0.65 | CYP1A2 (0.73) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL27905866 | 0.64 | CYP1A2 (0.48) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL19952765 | 0.64 | KDM4E (0.60) | CYP1A2HSD17B10KMT2AMEN1HPGD | |
| SCHEMBL10809246 | 0.64 | CYP1A2 (0.53) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL29025896 | 0.62 | CYP1A2 (0.61) | CYP1A2CYP3A4BRD4BRPF1CREBBP | |
| SCHEMBL28177075 | 0.59 | POLB (0.42) | CYP1A2CYP3A4BRD4BRPF1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |