Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.59 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.57 |
| ▸ | FBP1 | P09467 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045942 | 0.98 | — | — | |
| SCHEMBL7325816 | 0.98 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL17028600 | 0.76 | APOBEC3A (0.59) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL23571354 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL12344114 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL13063686 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL24869474 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL23666043 | 0.74 | APOBEC3A (1.00) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL2747663 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A | |
| SCHEMBL11772242 | 0.74 | APOBEC3A (0.57) | APOBEC3AAPOBEC3GPDK1FBP1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137426-A2 | 2-Mercaptothiazole derivatives, process for their preparation and utilization of 2-mercaptothiazole derivatives in pharmaceutical compounds | BAYER AG (DE) | 1985-04-17 | — | — | EP | disclosed |