Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031778 | 0.92 | MAPT (0.47) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL8657658 | 0.89 | MAPT (0.53) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL10965789 | 0.86 | MAPT (0.61) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL10992514 | 0.83 | MAPT (0.51) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL11030421 | 0.83 | MAPT (0.48) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL23391581 | 0.82 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL11026917 | 0.82 | ALOX5 (0.54) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL10963006 | 0.80 | MAPT (0.50) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL11029230 | 0.78 | MAPT (0.52) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 | |
| SCHEMBL10962795 | 0.78 | HTT (0.55) | MAPTSMN1; SMN2HPGDCYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050321-B1 | NOVEL BICYCLOOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND PESTICIDES CONTAINING THEM | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |