Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Crotonic Acid SCHEMBL10965681 | 1.00 | ITGB1 (0.37) | ITGB1ITGA5ITGB3ITGAVITGB2 | |
| Crotonic Acid SCHEMBL560763 | 0.69 | TSHR (0.57) | — | |
| Crotonic Acid SCHEMBL22034 | 0.69 | — | — | |
| Crotonic Acid SCHEMBL1080122 | 0.69 | TSHR (0.57) | — | |
| Crotonic Acid SCHEMBL28429 | 0.69 | — | — | |
| Crotonic Acid SCHEMBL1428157 | 0.69 | TSHR (0.57) | — | |
| Crotonic Acid SCHEMBL1427547 | 0.69 | TSHR (0.57) | — | |
| Crotonic Acid SCHEMBL167626 | 0.69 | TSHR (0.57) | — | |
| Crotonic Acid SCHEMBL22033 | 0.69 | — | — | |
| SCHEMBL9063425 | 0.68 | ITGB1 (0.52) | ITGB1ITGA5ITGB3ITGAVITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060119-B1 | AZETIDINONE COMPOUNDS AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1985-04-10 | — | — | EP | claimed |