Crotonic Acid

Crotonic Acid

SCHEMBL167626

C/C=C/C(=O)O.CC=CC(=O)O

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
TP53 P04637 1/20 0.57
EGLN1 Q9GZT9 1/20 0.57
EGLN3 Q9H6Z9 1/20 0.57
HCAR2 Q8TDS4 4/20 0.43
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41
GABRE P78334 2/20 0.41
GABRA6 Q16445 2/20 0.41
GABRG1 Q8N1C3 2/20 0.41
GABRG3 Q99928 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonic Acid SCHEMBL1428157 1.00 TSHR (0.57) TSHRTP53EGLN1EGLN3HCAR2
Crotonic Acid SCHEMBL22034 1.00
Crotonic Acid SCHEMBL28429 1.00
Crotonic Acid SCHEMBL560763 1.00 TSHR (0.57) TSHRTP53EGLN1EGLN3HCAR2
Crotonic Acid SCHEMBL22033 1.00
Crotonic Acid SCHEMBL1427547 1.00 TSHR (0.57) TSHRTP53EGLN1EGLN3HCAR2
Crotonic Acid SCHEMBL1080122 1.00 TSHR (0.57) TSHRTP53EGLN1EGLN3HCAR2
Crotonic Acid SCHEMBL8676950 0.96
Crotonic Acid SCHEMBL6909283 0.96
Crotonic Acid SCHEMBL6909279 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137746-B2 Elastomers THE PROCTER & GAMBLE COMPANY (US) 2012-03-20 US claimed
US-20120061866-A1 OPACIFYING POLYMERS AKZO NOBEL N.V. (NL) 2012-03-15 US claimed
US-8062758-B2 Process for producing self-stabilizing dispersion copolymer providing opacity to aqueous formulations AKZO NOBEL N.V. (NL) 2011-11-22 US claimed
US-20110098372-A1 FOAMABLE POLYAMIDES BASF SE (DE) 2011-04-28 US claimed
US-20110095227-A1 RETARDED SUPERABSORBENT POLYMERS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-04-28 US claimed
US-20110085995-A1 OPACIFYING POLYMERS AKZO NOBEL N.V. (NL) 2011-04-14 US claimed
US-7875359-B2 Self-stabilizing dispersion copolymer; polymerizable acid-containing compound, partially neutralized before or during polymerization, and a hydrophobic compound AKZO NOBEL N.V. (NL) 2011-01-25 US claimed
US-20110015285-A1 FOAMABLE COPOLYMERS BASED ON RENEWABLE RAW MATERIALS BASF SE (DE) 2011-01-20 US claimed
CN-119019245-A Preparation method of pharmaceutical grade 3-sodium hydroxybutyrate 上海康鑫化工有限公司 2024-11-26 CN disclosed
EP-2989107-B1 ACRYLIC COMPUND WITH TETRAOXASPIRO BACKBONE FOR RADIATION CURABLE COMPOSITIONS PERSTORP AB (SE) 2018-03-07 EP disclosed
EP-1886699-B1 Absorbent articles comprising superabsorbent polymers and a material with radiation-induced hydrophilicity PROCTER & GAMBLE (US) 2012-04-25 EP disclosed
EP-2440602-A1 SUPERABSORBENT POLYMER PARTICLES COATED WITH A HYDROPHILIC ELASTOMER AND ABSORBENT ARTICLE COMPRISING SUCH PARTICLES The Procter & Gamble Company (US) 2012-04-18 EP disclosed
US-8148312-B2 Method of treating a substrate with stable bleaches with coloring agents THE CLOROX COMPANY (US) 2012-04-03 US disclosed
US-20120078153-A1 WOUND DRESSINGS FIRST WATER RAMSBURY LIMITED (GB) 2012-03-29 US disclosed
US-20110015301-A1 MIXTURES COMPRISING BRANCHED OLIGOMERIC OR POLYMERIC COMPOUNDS, AND PREPARATION AND USE THEREOF BASF SE (DE) 2011-01-20 US disclosed
US-20110012057-A1 COATED SUPERABSORBENT POLYMER PARTICLES AND PROCESSES THEREFORE THE PROCTER & GAMBLE COMPANY (US) 2011-01-20 US disclosed
EP-1654011-B1 PROCESS FOR MAKING WATER-SWELLABLE MATERIAL COMPRISING COATED WATER-SWELLABLE POLYMERS PROCTER & GAMBLE (US) 2011-01-19 EP disclosed
US-7871640-B2 Surface cross-linked superabsorbent polymer particles and methods of making them THE PROCTER & GAMBLE COMPANY (US) 2011-01-18 US disclosed
US-20110004172-A1 Device for vacuum therapy of wounds PAUL HARTMANN AG (DE) 2011-01-06 US disclosed
US-20090092975-A1 SELECTABLE MARKER MOLOGIC LTD (GB) 2009-04-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092975-A1 SELECTABLE MARKER AMD1, PADI1, PSAT1 TSHR 3826/4885TP53 1982/4885EGLN1 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.