Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965707 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2744007 | 0.91 | CYP1A2 (0.52) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2744012 | 0.91 | CYP1A2 (0.52) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9113586 | 0.86 | ABCB1 (0.56) | KDM4EALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL9113609 | 0.86 | ABCB1 (0.56) | KDM4EALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL13168898 | 0.81 | KDM4E (0.76) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL8639752 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL8639756 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168900 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL13168901 | 0.78 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |