Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982576 | 0.79 | CHRM2 (0.58) | NPSR1LMNAALOX12HTTMEN1 | |
| SCHEMBL30858360 | 0.76 | ALDH1A1 (0.62) | NPSR1LMNAALOX12HTTMEN1 | |
| SCHEMBL6243579 | 0.76 | ALDH1A1 (0.62) | NPSR1LMNAALOX12HTTMEN1 | |
| SCHEMBL3960105 | 0.74 | ALDH1A1 (0.53) | NPSR1LMNAALOX12HTTMEN1 | |
| SCHEMBL10961892 | 0.74 | ALDH1A1 (0.38) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL23071620 | 0.73 | ALDH1A1 (0.43) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5026596 | 0.71 | CYP1A2 (0.41) | NPSR1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL30262675 | 0.71 | ALDH1A1 (0.39) | LMNAHTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7008960 | 0.70 | ALDH1A1 (0.52) | NPSR1LMNAALOX12HTTMEN1 | |
| SCHEMBL10651416 | 0.70 | TSHR (0.64) | LMNAKMT2AALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060955-B1 | SUBSTITUTED URACILS CONTAINING A 2-TETRAHYDROPYRANYL GROUP, PROCESS FOR THEIR PREPARATION AND PESTICIDAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1985-05-08 | — | — | EP | disclosed |
| EP-0060955-A1 | Substituted uracils containing a 2-tetrahydropyranyl group, process for their preparation and pesticidal compositions containing them | ROUSSEL-UCLAF (FR) | 1982-09-29 | — | — | EP | disclosed |