Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966530 | 1.00 | MEN1 (0.45) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10678087 | 0.90 | MEN1 (0.45) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10988836 | 0.89 | MEN1 (0.44) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10999445 | 0.89 | MEN1 (0.44) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10678091 | 0.88 | LMNA (0.46) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10981010 | 0.86 | MEN1 (0.45) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10735752 | 0.85 | MEN1 (0.47) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10735772 | 0.85 | MEN1 (0.47) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10678182 | 0.85 | MEN1 (0.41) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10682987 | 0.82 | MEN1 (0.46) | MEN1KMT2ACCKBRMAPTPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533660-A | Antibacterial O-sulfated β-lactam hydroxamic acids | E. R. SQUIBB & SONS, INC. (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0051381-B1 | O-SULFATED BETA-LACTAM HYDROXAMIC ACIDS | E.R. Squibb & Sons, Inc. (US) | 1985-01-30 | — | — | EP | disclosed |
| US-4337197-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0051381-A1 | O-sulfated beta-lactam hydroxamic acids | E.R. Squibb & Sons, Inc. (US) | 1982-05-12 | — | — | EP | disclosed |