Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045486 | 0.84 | SLC29A1 (0.68) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL11030143 | 0.84 | SLC29A1 (0.68) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL11026116 | 0.83 | SLC29A1 (0.66) | SLC29A1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL10970635 | 0.82 | SLC29A1 (0.47) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL10972595 | 0.82 | SLC29A1 (0.58) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL11026470 | 0.82 | SLC29A1 (0.36) | SLC29A1LMNANPSR1KDM4EALDH1A1 | |
| SCHEMBL10972553 | 0.80 | SLC29A1 (0.47) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL10663514 | 0.75 | HTT (0.38) | SLC29A1ADORA2ANPC1PKMLMNA | |
| SCHEMBL11049906 | 0.75 | HTT (0.38) | SLC29A1ADORA2ANPC1PKMLMNA | |
| SCHEMBL10971599 | 0.75 | HTT (0.38) | SLC29A1ADORA2ANPC1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055444-B1 | TRISUBSTITUTED PYRIMIDO(5,4-D)PYRIMIDINES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1985-03-20 | — | — | EP | disclosed |
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |