Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728411 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL11006226 | 0.84 | KMT2A (0.47) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL18508762 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL29006714 | 0.80 | TDP1 (0.55) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL6398309 | 0.79 | KMT2A (0.71) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL1094136 | 0.78 | KMT2A (0.65) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL16423099 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| Hydrochloric Acid SCHEMBL29079546 | 0.78 | KMT2A (0.69) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| Methane SCHEMBL28308571 | 0.78 | KMT2A (0.69) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB | |
| SCHEMBL7021564 | 0.77 | KMT2A (0.58) | ALDH1A1KMT2ASMN1; SMN2CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040932-B1 | AMIDE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-07-03 | — | — | EP | disclosed |
| US-4386080-A | 3,4-DISUBSTITUTED-N-ACYLANILINES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-31 | — | — | US | disclosed |
| EP-0040932-A1 | Amide derivatives, process for their manufacture and pharmaceutical or veterinary compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-12-02 | — | — | EP | disclosed |