Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18891775 | 0.81 | KCNJ11 (0.42) | MEN1KMT2AKCNJ11ABCC9ABCC8 | |
| SCHEMBL8171726 | 0.80 | NCEH1 (0.44) | LMNAKCNJ11ABCC9ABCC8KCNJ8 | |
| SCHEMBL27937799 | 0.79 | KCNH2 (0.42) | KCNJ11ABCC9ABCC8KCNJ8NCEH1 | |
| SCHEMBL11517897 | 0.78 | MEN1 (0.47) | KDM4EHPGDMEN1KMT2AKCNJ11 | |
| SCHEMBL18261804 | 0.76 | ACP3 (0.47) | ACP3KDM4ELMNAHPGDMEN1 | |
| SCHEMBL23367961 | 0.75 | KDM4E (0.43) | KDM4ELMNAMEN1KMT2AKCNJ11 | |
| SCHEMBL27680069 | 0.75 | KDM1A (0.46) | KDM4ELMNAHPGDMEN1KMT2A | |
| SCHEMBL887267 | 0.71 | KDM1A (0.51) | KDM4ELMNAHPGDMEN1KMT2A | |
| SCHEMBL29886792 | 0.71 | — | — | |
| SCHEMBL2167788 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0069622-B1 | PROCESS FOR THE PREPARATION OF BETA-CYCLO-SUBSTITUTED ETHYL AMINES, AND PRODUCTS SO OBTAINED | SANOFI S.A. (FR) | 1985-09-18 | — | — | EP | disclosed |