SCHEMBL887267

SCHEMBL887267

CCc1ccc2ccccc2c1Nc1ccc(C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.51
CDC25B P30305 1/20 0.44
UBE2I P63279 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
UBA2 Q9UBT2 1/20 0.44
HKDC1 Q2TB90 1/20 0.43
RAB9A P51151 2/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
HTT P42858 1/20 0.43
POLB P06746 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.40
KDM4A O75164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680069 0.89 KDM1A (0.46) KDM1ACDC25BHPGDSMN1; SMN2MAPT
SCHEMBL8171726 0.85 NCEH1 (0.44) HKDC1RAB9ANPC1SMN1; SMN2MAPT
SCHEMBL5461462 0.78 KDM1A (0.54) KDM1ACDC25BUBE2ISAE1UBA2
SCHEMBL31536849 0.77 KDM1A (0.54) KDM1ACDC25BUBE2ISAE1UBA2
SCHEMBL27937799 0.76 KCNH2 (0.42) ALDH1A1
SCHEMBL18134977 0.76 KDM1A (0.66) KDM1ACDC25BUBE2ISAE1UBA2
SCHEMBL10920351 0.76 KDM1A (0.43) KDM1ACDC25BHPGDMAPTKDM4E
SCHEMBL11517897 0.76 MEN1 (0.47) HPGDKDM4EALDH1A1GAAPOLB
SCHEMBL18891775 0.75 KCNJ11 (0.42) ALDH1A1MEN1KMT2A
SCHEMBL2177285 0.75 SNCA (0.50) KDM1ACDC25BUBE2ISAE1UBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863227-B2 High performance lubricant containing high molecular weight aromatic amine antioxidant and low boron content dispersant EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-01-04 US disclosed
US-20070232504-A1 High performance lubricant containing high molecular weight aromatic amine antioxidant and low boron content dispersant EXXONMOBIL RESEARCH AND ENGINEERING 2007-10-04 US disclosed