⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351115 | 0.78 | — | — | |
| SCHEMBL11098714 | 0.73 | FAAH (0.30) | — | |
| SCHEMBL10969697 | 0.72 | — | — | |
| SCHEMBL10999628 | 0.71 | — | — | |
| SCHEMBL9878135 | 0.70 | — | — | |
| SCHEMBL3336728 | 0.69 | — | — | |
| SCHEMBL11220164 | 0.69 | — | — | |
| SCHEMBL3335547 | 0.68 | ELANE (0.31) | — | |
| SCHEMBL10965368 | 0.66 | — | — | |
| SCHEMBL11052400 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037080-B1 | 4-(3-CARBOXY-2-OXOPROPYL)-AZETIDINO-2-ONES AND PROCESS FOR THEIR PREPARATION | MERCK & CO. INC. (US) | 1985-03-13 | — | — | EP | disclosed |
| EP-0038869-A1 | Process for the preparation of 1-carbapenems, and intermediates for their preparation | MERCK & CO. INC. (US) | 1981-11-04 | — | — | EP | disclosed |
| EP-0037080-A1 | 4-(3-carboxy-2-oxopropyl)-azetidino-2-ones and process for their preparation | MERCK & CO. INC. (US) | 1981-10-07 | — | — | EP | disclosed |