Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.59 |
| ▸ | ITGAL | P20701 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836292 | 1.00 | ITGB1 (0.59) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9836299 | 1.00 | ITGB1 (0.59) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10999787 | 0.87 | ITGB1 (0.53) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9377695 | 0.82 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11307625 | 0.81 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565414 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565344 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565345 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11062751 | 0.77 | — | — | |
| SCHEMBL10104800 | 0.75 | GAA (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4539152-A | INTERMEDIATES FOR THIENAMYCIN ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0051234-B1 | A PROCESS FOR THE PRODUCTION OF A 2-AZETIDINONE DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-03-13 | — | — | EP | disclosed |
| EP-0035689-B1 | 4-SUBSTITUTED-2-OXOAZETIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE FOR PREPARING ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-19 | — | — | EP | disclosed |
| EP-0090340-A1 | Process for preparation of optically active 4-(2-Hydroxyethyl)-2-azetidinone | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4383945-A | 4-Substituted-2-oxoazetidine compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0051234-A1 | A process for the production of a 2-azetidinone derivative | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-05-12 | — | — | EP | disclosed |
| EP-0035689-A1 | 4-Substituted-2-oxoazetidine compounds, processes for their preparation, and their use for preparing antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-16 | — | — | EP | disclosed |