Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.59 |
| ▸ | ITGAV | P06756 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.59 |
| ▸ | ITGAL | P20701 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968083 | 1.00 | ITGB1 (0.59) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9836299 | 1.00 | ITGB1 (0.59) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10999787 | 0.87 | ITGB1 (0.53) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL9377695 | 0.82 | ITGB1 (0.61) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11307625 | 0.81 | ITGB1 (0.55) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565414 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565344 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL21565345 | 0.79 | GAA (0.41) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL11062751 | 0.77 | — | — | |
| SCHEMBL10104800 | 0.75 | GAA (0.39) | ITGB1ITGA5ITGB3ITGB2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58198492-A | — | — | None | — | — | JP | disclosed |
| EP-0197491-B1 | 3-OXO-2-AZABICYCLOHEXANE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND USE OF SAID DERIVATIVES AS INTERMEDIATES FOR ANTIBACTERIAL AGENTS | Eisai Co., Ltd. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4754029-A | 3-oxo-2-azabicyclohexane derivatives | EISAI CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0197491-A1 | 3-oxo-2-azabicyclohexane derivatives, process for the production thereof and use of said derivatives as intermediates for antibacterial agents | Eisai Co., Ltd. (JP) | 1986-10-15 | — | — | EP | disclosed |
| US-4511509-A | CARBAPENICILLIN INTERMEDIATES | KOWA CO. LTD. (JP) | 1985-04-16 | — | — | US | disclosed |
| US-4506085-A | AMINATION, INTERMEDIATE FOR ANTIBIOTICS | SANRAKU-OCEAN CO., LTD. (JP) | 1985-03-19 | — | — | US | disclosed |
| EP-0051234-B1 | A PROCESS FOR THE PRODUCTION OF A 2-AZETIDINONE DERIVATIVE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-03-13 | — | — | EP | disclosed |
| EP-0050799-B1 | NEW PROCESSES FOR THE PRODUCTION OF DI-ALKYL ESTERS AND OPTICALLY ACTIVE MONO-ALKYL ESTERS OF 3-AMINOGLUTARIC ACID | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1984-12-19 | — | — | EP | disclosed |
| JP-S58198492-A | NOVEL AZETIDINE DERIVATIVE AND ITS PREPARATION | KOWA CO | 1983-11-18 | — | — | JP | disclosed |
| EP-0091239-A1 | Azetidine derivatives and a process for their production | KOWA COMPANY, LTD. (JP) | 1983-10-12 | — | — | EP | disclosed |
| EP-0090340-A1 | Process for preparation of optically active 4-(2-Hydroxyethyl)-2-azetidinone | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0050799-A1 | New processes for the production of di-alkyl esters and optically active mono-alkyl esters of 3-aminoglutaric acid | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-05-05 | — | — | EP | disclosed |