Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 6/20 | 0.84 |
| ▸ | MEN1 | O00255 | 9/20 | 0.82 |
| ▸ | THRB | P10828 | 9/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.82 |
| ▸ | BLM | P54132 | 8/20 | 0.82 |
| ▸ | RECQL | P46063 | 7/20 | 0.82 |
| ▸ | BRCA1 | P38398 | 6/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.82 |
| ▸ | USP2 | O75604 | 4/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.82 |
| ▸ | TOP2A | P11388 | 4/20 | 0.82 |
| ▸ | HTT | P42858 | 4/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.82 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943294 | 1.00 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL14164316 | 1.00 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| Hydrochloric Acid SCHEMBL11279876 | 0.99 | S100A4 (0.83) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL26358705 | 0.96 | S100A4 (0.83) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL248564 | 0.95 | S100A4 (0.85) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL319890 | 0.94 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL3763974 | 0.94 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| Hydrochloric Acid SCHEMBL331063 | 0.94 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| SCHEMBL11563422 | 0.94 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM | |
| Hydrochloric Acid SCHEMBL28160744 | 0.94 | S100A4 (0.84) | S100A4MEN1THRBKMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54141759-A | — | — | None | — | — | JP | disclosed |
| US-8846882-B2 | Method of producing 4-demethoxydaunorubicin | SYNBIAS PHARMA AG (CH) | 2014-09-30 | — | — | US | disclosed |
| EP-0051279-B1 | ANTHRACYCLINE GLYCOSIDES, INTERMEDIATE COMPOUNDS, PROCESS FOR PREPARING BOTH AND PHARMACEUTICAL COMPOSITIONS | FARMITALIA CARLO ERBA S.p.A. (IT) | 1985-09-04 | — | — | EP | disclosed |
| JP-S54141759-A | NOVEL ANTHRACYCLINE DERIVATIVE | MICROBIAL CHEM RES FOUND | 1979-11-05 | — | — | JP | disclosed |